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86-4048-96 4&x2F;DLL4 C-Fc 50ug PKSH034030 アズワン Recombinant Human Delta-like Protein 人気ショップ

86-4048-96Recombinant Human Delta-like Protein 4DLL4 C-Fc 50ug PKSH034030 人気ショップ

Protein Delta-like Human 86-4048-96Recombinant アズワン 86-4048-96 4&x2F;DLL4 C-Fc 50ug PKSH034030 アズワン Recombinant Human Delta-like Protein 人気ショップ 86-4048-96Recombinant Human Delta-like Protein 4DLL4 C-Fc 50ug PKSH034030 人気ショップ hQ7wIUKCRpsSO9M 56000円 syntaxis210-k0o8chjkw konidelaproductioncompany.com シルエットがとても綺麗で高級感がありますが、 試薬 タンパク質因子 組み換えタンパク質 86-4048-96 Recombinant Human Delta-like Protein 4&x2F;DLL4 C-Fc 50ug PKSH034030 PKSH034030 50ug C-Fc 4DLL4 Protein Delta-like Human 86-4048-96Recombinant アズワン 86-4048-96 4&x2F;DLL4 C-Fc 50ug PKSH034030 アズワン Recombinant Human Delta-like Protein 人気ショップ 86-4048-96Recombinant Human Delta-like Protein 4DLL4 C-Fc 50ug PKSH034030 人気ショップ hQ7wIUKCRpsSO9M 56000円 syntaxis210-k0o8chjkw konidelaproductioncompany.com シルエットがとても綺麗で高級感がありますが、 試薬 タンパク質因子 組み換えタンパク質 86-4048-96 Recombinant Human Delta-like Protein 4&x2F;DLL4 C-Fc 50ug PKSH034030 PKSH034030 50ug C-Fc 4DLL4 Protein Delta-like Human 86-4048-96Recombinant アズワン

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特徴

  • 背景:Delta-like protein 4 (DLL4) is a type I membrane protein belonging to the Delta/Serrate/Lag2 (DSL) family of Notch ligands. In mammals, four Notch homologs (Notch 1 to4) and five ligands (DLL 1, 3 and 4, Jagged 1 and 2) have been identified. DLL4 is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch 1 and Notch 4. Human and mouse DLL4 shares 86% amino acid sequence identity. Notch ligands are transmembrane proteins with a DSL motif necessary for Notch binding, tandem EGF repeats, a transmembrane region and a short intracellular domain (ICD). Notch ligands are categorized into two subfamilies based on the presence of an extracellular cysteinerich domain and insertions that interrupt some EGF repeats in the Jagged but not the Delta ligand family. Interactions of Notch receptors with their ligands result in reciprocal regulated intramembrane proteolysis (RIP). RIP is a mechanism for transmembrane signal transduction that involves the sequential processing by a disintegrin metalloprotease (ADAM) and then by presenilin/ γ secretase, resulting in shedding of the extracellular domains and the generation of the soluble ICD signaling fragments, respectively.

仕様

  • 種由来:Human
  • 発現宿主:Human Cells
  • 純度:>95% as determined by reducing SDS-PAGE.
  • 遺伝子構造:Recombinant Human Delta-like Protein 4 is produced by our Mammalian expression system and the target gene encoding Ser27-Pro524 is expressed with a Fc tag at the C-terminus.
  • 別名(遺伝子名):Delta-like protein 4; Drosophila Delta homolog 4; Delta4; DLL4
  • アミノ酸配列:Ser27-Pro524
  • アクセッションNo.:Q9NR61
  • タグ種類:C-Fc
  • エンドトキシン濃度:< 1.0 EU per ug as determined by the LAL method.
  • 分子量:81.2 kDa
  • 組成:Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
  • 保存条件:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
  • メーカーマニュアルリンク:https://u2.elabscience.com/viewpdf-463494-elabscience-PKSH034030.pdf
  • サイズ:50ug
  • この商品は法規制を確認しておりません。 (法規制によって販売できない場合もございます)
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